MICROWAVE-ASSISTED EXTRACTION OF PHENOLIC COMPOUNDS FROM CARICA PAPAYA LEAVES: AN OPTIMIZATION STUDY AND LC-QTOF-MS ANALYSIS

Microwave-assisted extraction of phenolic compounds from Carica papaya leaves: An optimization study and LC-QTOF-MS analysis

Carica papaya is a well-known plant with diverse importance to human beings.The efficacy of microwave-assisted extraction (MAE) in the recovery of phenolic compounds from C.papaya leaf was investigated in this study.The MAE process variables were optimized using response surface method; at the optimized conditions, the embedded phenolic compounds i

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Alterations in leukocyte DNA methylome are associated to immunosuppression in severe clinical phenotypes of septic patients

IntroductionSepsis patients experience a complex interplay of host pro- and anti-inflammatory processes which compromise the clinical outcome.Despite considering the latest clinical and scientific research, our comprehension of the immunosuppressive events in septic episodes remains incomplete.Additionally, a lack of data exists regarding the role

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